Extremis (storyline)

Extremis is a Marvel Comics storyline featuring Iron Man. Designed as a jumping on point for new readers, it takes the series into more of a cyberpunk inspired direction, exploring the Frankenstein-ian implications of technology creating super-powered beings.

Plot Summary
Iron Man investigates the theft of a sample of Extremis, a nanotech designer virus that rewrites a subject's genetic code, granting them superhuman powers. When the sample ends up in the hands of a dangerous extremist, Iron Man is faced with a foe who very nearly brings him to death's door.